Pathway Ontology / 通路本体

Last uploaded: September 7, 2023
Preferred Name

peroxisome proliferator-activated receptor signaling pathway

Synonyms

peroxisome proliferator activated receptor signaling pathway

PPAR signaling pathway

Definitions

Peroxisome proliferator-activated receptor signaling is initiated in response to binding several compounds within classes of lipids such as the eicosanoids, leukotrienes and prostagladins, among others. The receptors form heterodimers with the retinoid X receptor, bind to specific DNA elements and regulate the expression of target genes. Deregulation of the pathway has been implicated in several conditions.

ID

http://purl.obolibrary.org/obo/PW_0001355

created_by

VPetri

creation_date

2013-06-05T08:45:28Z

definition

Peroxisome proliferator-activated receptor signaling is initiated in response to binding several compounds within classes of lipids such as the eicosanoids, leukotrienes and prostagladins, among others. The receptors form heterodimers with the retinoid X receptor, bind to specific DNA elements and regulate the expression of target genes. Deregulation of the pathway has been implicated in several conditions.

has_exact_synonym

PPAR signaling pathway

has_obo_namespace

pathway

has_related_synonym

peroxisome proliferator activated receptor signaling pathway

id

PW:0001355

label

peroxisome proliferator-activated receptor signaling pathway

notation

PW:0001355

prefLabel

peroxisome proliferator-activated receptor signaling pathway

treeView

http://purl.obolibrary.org/obo/PW_0001313

http://purl.obolibrary.org/obo/PW_0000716

subClassOf

http://purl.obolibrary.org/obo/PW_0001313

http://purl.obolibrary.org/obo/PW_0000716

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http://purl.obolibrary.org/obo/GO_0035357 Gene Ontology / 基因本体 LOOM