loading...| Preferred Name |
CD4 Antigens |
| Synonyms |
Receptors, CD4 |
| Definitions |
55-kDa antigens found on HELPER-INDUCER T-LYMPHOCYTES and on a variety of other immune cell types. They are members of the immunoglobulin supergene family and are implicated as associative recognition elements in MAJOR HISTOCOMPATIBILITY COMPLEX class II-restricted immune responses. On T-lymphocytes they define the helper/inducer subset. T4 antigens also serve as INTERLEUKIN-15 receptors and bind to the HIV receptors, binding directly to the HIV ENVELOPE PROTEIN GP120. |
| ID |
http://purl.bioontology.org/ontology/MESH/D015704 |
| altLabel |
Receptors, CD4 CD4 Receptor, Surface T4 Antigens, T-Cell Antigens, CD4 Receptors, Surface CD4 CD4 Molecule T-Cell T4 Antigens Receptor, CD4 Antigen, CD4 Surface CD4 Receptors CD4 Receptors, Surface Surface CD4 Receptor Antigens, T-Cell T4 CD4 Receptor CD4 Antigen T4 Antigens, T Cell CD4 Receptors |
| AN |
for hematodermic CD4/CD56 neoplasm use LYMPHOMA, NON-HODGKIN |
| AQL |
AD AG AI AN BI BL CH CL DE DF GE HI IM IP ME PH RE TU UL |
| cui |
C0003323 |
| DC |
1 |
| definition |
55-kDa antigens found on HELPER-INDUCER T-LYMPHOCYTES and on a variety of other immune cell types. They are members of the immunoglobulin supergene family and are implicated as associative recognition elements in MAJOR HISTOCOMPATIBILITY COMPLEX class II-restricted immune responses. On T-lymphocytes they define the helper/inducer subset. T4 antigens also serve as INTERLEUKIN-15 receptors and bind to the HIV receptors, binding directly to the HIV ENVELOPE PROTEIN GP120. |
| DX |
19900101 |
| FX |
D000070557 D015699 D016516 |
| HN |
2018 (1989); use ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE 1989 |
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000528 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000172 |
| Inverse of RB |
0 |
| Inverse of RO |
http://purl.bioontology.org/ontology/MESH/D015699 http://purl.bioontology.org/ontology/MESH/D000070557 |
| Machine permutation |
2018; see ANTIGENS, CD4 1990-2017 and ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE 1989 |
| Mapped from |
http://purl.bioontology.org/ontology/MESH/C076613 http://purl.bioontology.org/ontology/MESH/C056725 http://purl.bioontology.org/ontology/MESH/C063735 http://purl.bioontology.org/ontology/MESH/C086848 http://purl.bioontology.org/ontology/MESH/C402366 http://purl.bioontology.org/ontology/MESH/C081945 |
| MDA |
19890619 |
| MMR |
20210630 |
| MN |
D12.776.543.750.830.700.025 D23.101.100.894.100 D12.776.543.750.705.852.420.810.500 D23.050.301.264.894.100 |
| notation |
D015704 |
| prefLabel |
CD4 Antigens |
| TERMUI |
T046552 T001090066 T046557 T046555 T046558 T046553 T046560 T046554 T046559 T046556 |
| TH |
NLM (1993) NLM (1992) NLM (1990) NLM (1994) NLM (2022) |
| tui |
T116 T129 T192 |
| subClassOf |
http://purl.bioontology.org/ontology/MESH/D000945 |