Gene Ontology / 基因本体

Last uploaded: August 7, 2023
Preferred Name

toll-like receptor signaling pathway

Synonyms

TLR signaling pathway

toll-like receptor signalling pathway

Definitions

Note that the vertebrate toll-like receptors, unlike the Drosophila Toll molecule, directly bind their ligands. The Drosophila Toll molecule requires the Sptzle factor to bind microbial ligands and then the receptor in order to initiate innate immune responses. The series of molecular signals initiated by a ligand binding to a toll-like receptor of a target cell. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate an innate immune response.

ID

http://purl.obolibrary.org/obo/GO_0002224

comment

Note that the vertebrate toll-like receptors, unlike the Drosophila Toll molecule, directly bind their ligands. The Drosophila Toll molecule requires the Sptzle factor to bind microbial ligands and then the receptor in order to initiate innate immune responses.

definition

The series of molecular signals initiated by a ligand binding to a toll-like receptor of a target cell. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate an innate immune response.

has_exact_synonym

TLR signaling pathway

toll-like receptor signalling pathway

has_obo_namespace

biological_process

id

GO:0002224

label

toll-like receptor signaling pathway

notation

GO:0002224

prefLabel

toll-like receptor signaling pathway

treeView

http://purl.obolibrary.org/obo/GO_0002221

subClassOf

http://purl.obolibrary.org/obo/GO_0002221

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http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C91505 National Cancer Institute Thesaurus / 美国国家癌症研究所词典 LOOM
http://purl.obolibrary.org/obo/PW_0000814 Pathway Ontology / 通路本体 LOOM