| Preferred Name |
toll-like receptor signaling pathway |
| Synonyms |
TLR signaling pathway toll-like receptor signalling pathway |
| Definitions |
Note that the vertebrate toll-like receptors, unlike the Drosophila Toll molecule, directly bind their ligands. The Drosophila Toll molecule requires the Sptzle factor to bind microbial ligands and then the receptor in order to initiate innate immune responses. The series of molecular signals initiated by a ligand binding to a toll-like receptor of a target cell. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate an innate immune response. |
| ID |
http://purl.obolibrary.org/obo/GO_0002224 |
| comment |
Note that the vertebrate toll-like receptors, unlike the Drosophila Toll molecule, directly bind their ligands. The Drosophila Toll molecule requires the Sptzle factor to bind microbial ligands and then the receptor in order to initiate innate immune responses. |
| definition |
The series of molecular signals initiated by a ligand binding to a toll-like receptor of a target cell. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate an innate immune response. |
| has_exact_synonym |
TLR signaling pathway toll-like receptor signalling pathway |
| has_obo_namespace |
biological_process |
| id |
GO:0002224 |
| label |
toll-like receptor signaling pathway |
| notation |
GO:0002224 |
| prefLabel |
toll-like receptor signaling pathway |
| treeView | |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C91505 | National Cancer Institute Thesaurus / 美国国家癌症研究所词典 | LOOM | |
| http://purl.obolibrary.org/obo/PW_0000814 | Pathway Ontology / 通路本体 | LOOM |