A key regulator of CELL CYCLE progression. It partners with CYCLIN E to regulate entry into S PHASE and also interacts with CYCLIN A to phosphorylate RETINOBLASTOMA PROTEIN. Its activity is inhibited by CYCLIN-DEPENDENT KINASE INHIBITOR P27 and CYCLIN-DEPENDENT KINASE INHIBITOR P21.
ID
http://purl.bioontology.org/ontology/MESH/D051357
altLabel
Cyclin Dependent Kinase 2
p33cdk2 Kinase
Cdk2 Protein Kinase
Cdc2 Related Protein Kinase
CDK2 Protein
Cdc2-Related Protein Kinase
AQL
AD AE AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
cui
C1533646
DC
1
definition
A key regulator of CELL CYCLE progression. It partners with CYCLIN E to regulate entry into S PHASE and also interacts with CYCLIN A to phosphorylate RETINOBLASTOMA PROTEIN. Its activity is inhibited by CYCLIN-DEPENDENT KINASE INHIBITOR P27 and CYCLIN-DEPENDENT KINASE INHIBITOR P21.
2006; CYCLIN-DEPENDENT KINASE 2 was indexed under CDC2-CDC28 KINASES 2004-2005, & under CYCLIN-DEPENDENT KINASES 1991-2003, & under PROTEIN KINASES 1991-1994
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