loading...| Preferred Name |
delanzomib |
| Synonyms |
delanzomibum [(1R)-3-methyl-1-({N-[(6-phenylpyridin-2-yl)carbonyl]-L-threonyl}amino)butyl]boronic acid CEP-18770 CT-47098 boronic acid, ((1R)-1-(((2S,3R)-3-hydroxy-1-oxo-2-(((6-phenyl-2-pyridinyl)carbonyl)amino)butyl)amino)-3-methylbutyl)- delanzomib [(1R)-1-[[(2S,3R)-3-hydroxy-2-[(6-phenylpyridin-2-yl)carbonylamino]butanoyl]amino]-3-methyl-butyl]boronic acid [(1R)-1-[[(2S,3R)-3-hydroxy-1-oxo-2-[[oxo-(6-phenyl-2-pyridyl)methyl]amino]butyl]amino]-3-methylbutyl]boronic acid |
| Definitions |
A C-terminal boronic acid peptide inhibitor which induces apoptosis in multiple myeloma, hematological and solid tumor cell lines. |
| ID |
http://purl.obolibrary.org/obo/CHEBI_141530 |
| charge |
0 |
| database_cross_reference |
PMID:29371974 PMID:19958357 CAS:847499-27-8 PMID:28140719 Patent:WO2011087822 PMID:20872901 DrugBank:DB11956 Reaxys:12211043 KEGG:D10110 PMID:18057228 PMID:29848702 PMID:22906694 PMID:22178195 PMID:23058787 |
| definition |
A C-terminal boronic acid peptide inhibitor which induces apoptosis in multiple myeloma, hematological and solid tumor cell lines. |
| formula |
C21H28BN3O5 |
| has functional parent | |
| has role |
http://purl.obolibrary.org/obo/CHEBI_52726 |
| has_exact_synonym |
[(1R)-3-methyl-1-({N-[(6-phenylpyridin-2-yl)carbonyl]-L-threonyl}amino)butyl]boronic acid |
| has_obo_namespace |
chebi_ontology |
| has_related_synonym |
delanzomibum CEP-18770 CT-47098 boronic acid, ((1R)-1-(((2S,3R)-3-hydroxy-1-oxo-2-(((6-phenyl-2-pyridinyl)carbonyl)amino)butyl)amino)-3-methylbutyl)- delanzomib [(1R)-1-[[(2S,3R)-3-hydroxy-2-[(6-phenylpyridin-2-yl)carbonylamino]butanoyl]amino]-3-methyl-butyl]boronic acid [(1R)-1-[[(2S,3R)-3-hydroxy-1-oxo-2-[[oxo-(6-phenyl-2-pyridyl)methyl]amino]butyl]amino]-3-methylbutyl]boronic acid |
| id |
CHEBI:141530 |
| in_subset | |
| inchi |
InChI=1S/C21H28BN3O5/c1-13(2)12-18(22(29)30)24-21(28)19(14(3)26)25-20(27)17-11-7-10-16(23-17)15-8-5-4-6-9-15/h4-11,13-14,18-19,26,29-30H,12H2,1-3H3,(H,24,28)(H,25,27)/t14-,18+,19+/m1/s1 |
| inchikey |
SJFBTAPEPRWNKH-CCKFTAQKSA-N |
| label |
delanzomib |
| mass |
413.276 |
| monoisotopicmass |
413.21220 |
| notation |
CHEBI:141530 |
| prefLabel |
delanzomib |
| smiles |
O=C(N[C@H](C(=O)N[C@@H](CC(C)C)B(O)O)[C@H](O)C)C1=NC(C2=CC=CC=C2)=CC=C1 |
| treeView |
http://purl.obolibrary.org/obo/CHEBI_26987 http://purl.obolibrary.org/obo/CHEBI_35681 |
| subClassOf |
http://purl.obolibrary.org/obo/CHEBI_26987 http://purl.obolibrary.org/obo/CHEBI_35681 |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| There are currently no mappings for this class. | |||