| Preferred Name |
peroxisome proliferator-activated receptor signaling pathway |
| Synonyms |
peroxisome proliferator activated receptor signaling pathway PPAR signaling pathway |
| Definitions |
Peroxisome proliferator-activated receptor signaling is initiated in response to binding several compounds within classes of lipids such as the eicosanoids, leukotrienes and prostagladins, among others. The receptors form heterodimers with the retinoid X receptor, bind to specific DNA elements and regulate the expression of target genes. Deregulation of the pathway has been implicated in several conditions. |
| ID |
http://purl.obolibrary.org/obo/PW_0001355 |
| created_by |
VPetri |
| creation_date |
2013-06-05T08:45:28Z |
| definition |
Peroxisome proliferator-activated receptor signaling is initiated in response to binding several compounds within classes of lipids such as the eicosanoids, leukotrienes and prostagladins, among others. The receptors form heterodimers with the retinoid X receptor, bind to specific DNA elements and regulate the expression of target genes. Deregulation of the pathway has been implicated in several conditions. |
| has_exact_synonym |
PPAR signaling pathway |
| has_obo_namespace |
pathway |
| has_related_synonym |
peroxisome proliferator activated receptor signaling pathway |
| id |
PW:0001355 |
| label |
peroxisome proliferator-activated receptor signaling pathway |
| notation |
PW:0001355 |
| prefLabel |
peroxisome proliferator-activated receptor signaling pathway |
| treeView | |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.obolibrary.org/obo/GO_0035357 | Gene Ontology / 基因本体 | LOOM |