Preferred Name

Dimercaprol

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47494

CAS_Registry

59-52-9

CHEBI_ID

CHEBI:64198

Chemical_Formula

C3H8OS2

code

C47494

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A metal chelating agent that is used as an antidote in arsenic, gold, lead, mercury and other heavy metal poisoning. Metals form ligands in the body with the sulfhydryl groups of the pyruvate-oxidase enzyme system. This leads to an inhibition of the normal functioning of these enzymes that are dependent on free sulfhydryl groups for their activity. Dimercaprol reverses the enzyme inhibition by chelating the metal and regenerates free sulfhydryl groups, thereby preventing and reversing the metals toxic effects.

FDA_UNII_Code

0CPP32S55X

FULL_SYN

1,2-Dithioglycerol

Dimercaprol

BAL in Oil

2,3-Dimercapto-1-propanol

DIMERCAPROL

label

Dimercaprol

Legacy Concept Name

Dimercaprol

NSC Number

39515

Preferred_Name

Dimercaprol

prefixIRI

Thesaurus:C47494

prefLabel

Dimercaprol

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0012383

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C360

Delete Subject Author Type Created
No notes to display
Create New Mapping

Delete Mapping To Ontology Source
http://purl.bioontology.org/ontology/ATC/V03AB09 Anatomical Therapeutic Chemical Classification / 解剖学治疗学及化学分类系统 LOOM
http://purl.obolibrary.org/obo/CHEBI_64198 Chemical Entities of Biological Interest Ontology / 生物相关的化学实体本体 LOOM
http://purl.obolibrary.org/obo/CHEBI_64198 The Drug Ontology / 药物本体 LOOM
http://purl.obolibrary.org/obo/CHEBI_64198 Experimental Factor Ontology / 实验性因素本体 LOOM
http://purl.bioontology.org/ontology/MESH/D004112 Medical Subject Headings / 医学主题词表 LOOM