loading...| Preferred Name |
Protoporphyrinogen Oxidase |
| Synonyms |
Protox |
| Definitions |
A membrane-bound flavoenzyme that catalyzes the oxygen-dependent aromatization of protoporphyrinogen IX (Protogen) to protoporphyrin IX (Proto IX). It is the last enzyme of the common branch of the HEME and CHLOROPHYLL pathways in plants, and is the molecular target of diphenyl ether-type herbicides. VARIEGATE PORPHYRIA is an autosomal dominant disorder associated with deficiency of protoporphyrinogen oxidase. |
| ID |
http://purl.bioontology.org/ontology/MESH/D050768 |
| altLabel |
Protox Protoporphyrinogen IX Oxidase Oxidase, Protoporphyrinogen Protoporphyrinogen Dehydrogenase Protoporphyrinogenase Oxidase, Protoporphyrinogen IX Dehydrogenase, Protoporphyrinogen |
| AQL |
AD AE AI AN BI BL CF CH CL CS DE EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR |
| cui |
C0072500 |
| DC |
1 |
| definition |
A membrane-bound flavoenzyme that catalyzes the oxygen-dependent aromatization of protoporphyrinogen IX (Protogen) to protoporphyrin IX (Proto IX). It is the last enzyme of the common branch of the HEME and CHLOROPHYLL pathways in plants, and is the molecular target of diphenyl ether-type herbicides. VARIEGATE PORPHYRIA is an autosomal dominant disorder associated with deficiency of protoporphyrinogen oxidase. |
| DX |
20060101 |
| EC |
deficiency:Porphyria, Variegate |
| HN |
2006(1975) |
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000528 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000378 |
| Inverse of RB |
EC 1.3.3.4 |
| Machine permutation |
2006; PROTOPORPHYRINOGEN OXIDASE was indexed under OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS 2004-2005, under OXIDOREDUCTASES 1993-2003, under PORPHYRINS 1975-1976, and under PROTOPORPHYRINS 1975-1982 |
| Mapped from |
http://purl.bioontology.org/ontology/MESH/C587504 http://purl.bioontology.org/ontology/MESH/C493979 http://purl.bioontology.org/ontology/MESH/C493976 |
| MDA |
20050630 |
| MMR |
20090715 |
| MN |
D08.811.682.660.600 D12.776.543.697 |
| notation |
D050768 |
| prefLabel |
Protoporphyrinogen Oxidase |
| TERMUI |
T108572 T108574 T108571 T623808 T108570 |
| TH |
NLM (2006) |
| tui |
T116 T126 |
| subClassOf |